Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells

Fischer, S#; Trinh, V. T.#; Simon, C.; Weber, L. M.; Forné, I.; Nist, A. Bange, G.; Abendroth, F.; Stiewe, T.; Steinchen, W.; Liefke, R*. Vázquez, O.*; ( # Equal 1st author contribution)

Cell Chem. Bo 2023, 30, 766-779

Reported in:

  • Marburg University (23.06.2023)
  • Hessenshau (28.06.2023)
  • Mediziner Aspekete (23.06.2023)
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells

Reversible Control of RNA Splicing by Photoswitchable Small Molecules

Zhang, L.; Xiulan X.; Djokovic N.; Nikolic, K.; Kosenkov, D.; Abendroth, F.*; Vázquez, O*

J. Am Chem. Soc. 145, 12783-12792

Reversible Control of RNA Splicing by Photoswitchable Small Molecules

EFMC: Trends in Medicinal Chemistry and Chemical Biology

Auberson, P.Y.*, Arimondo, P. B.; Duca, M.; Essig, S.; Grether, U.; Rufer, A. C.; Sbardella, G.; Shopfer, U.; Torrens, A.; van der Stelt, M; Vauzeilles, B.; Vázquez, O.; Zhang, A. X.

 Chem.Bio. 2023, 24, e20220069

EFMC: Trends in Medicinal Chemistry and Chemical Biology

Synthesis of the L- and D-SH2 domain of the leukaemia oncogene Bcr-Abl

Schmidt, N.; Abendroth, F.; Vázquez, O.*, Hantschel, O.*

RSC Chem. Biol., 2022, 3, 1008-1012

Synthesis of the L- and D-SH2 domain of the leukaemia oncogene Bcr-Abl

Increasing the efficiency of hyperthermic intraperitoneal chemotherapy (HIPEC) by a combination with a photosensitive drug in pediatric rhabdomyosarcoma

Wagner, B.; Adamus, A.; Hempfling, L., Vahdad, R.; Haap-Hoff, A.; Heinrich, B.; Vázquez, O.; Jank, P.; Denkert, C.; Seitz, G*

Pediatr. Blood Cancer, 2022, 11, e29864

Increasing the efficiency of hyperthermic intraperitoneal chemotherapy (HIPEC) by a combination with a photosensitive drug in pediatric rhabdomyosarcoma

A chemical biology perspective to therapeutic regulation of RNA splicing in spinal muscular atrophy (SMA)

Zhang, L.; Abendroth, F.; Vázquez, O.*

ACS. Chem. Biol., 2022, 17, 1293 -1307

A chemical biology perspective to therapeutic regulation of RNA splicing in spinal muscular atrophy (SMA)

RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling and nucleosome remodeling

Ullah I.; Thoelken, C.; Zhong, Y.; John, M.; Rossbach, O.; Lenz, J.;Großringer, M.; Nist, A.; Stiewe, T.; Hartmann, R.; Vázquez, O.; Chung,H.-R; Machkay, J.P.; Brehm, A.*

Cell. Rep., 2022, accepted,

RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling and nucleosome remodeling

Bistable photoswitch allows in vivo control of hematopoiesis

Albert, L.; Nagpal, J.; Steinchen, W.; Zhang, L.; Werel, L.; Djokovic N.; Ruzic, D.; Hoffarth, M.; Xu, J.; Kaspareit, J.; Abendroth, F.; Royant, A.; Bange, G.; Nikolic, K.; Ryu, S.; Dou, Y.; Essen, L.-O.; Vázquez, O*

ACS Cent. Sci, 2022, ,57-66

Bistable photoswitch allows in vivo control of hematopoiesis

Efficient antisense inhibition reveals microRNA-155 to restrain a latemyeloid inflammatory programme in primary human phagocytes

Linden, G.; Harshavardhan, J.; Matthias, F.; Nist, A.; Stiewe, T.; Schmeck B.; Vázquez, O*.; Shulte, L. N.*

RNA Biol., 2021, 18 ,604-618

Efficient antisense inhibition reveals microRNA-155 to restrain a latemyeloid inflammatory programme in primary human phagocytes

Targeted protein degradation as a promising tool for epigenetic upregulation of fetal hemoglobin

Verheul, T. C. J.; Trinh, V. T.; Vázquez, O.* ; Philipsen, S*

MedChemMed, 2020, 15, 2436-2443

Contribution to the Special Chemical Epigenetics Themed Issue in ChemMedChem

Targeted protein degradation as a promising tool for epigenetic upregulation of fetal hemoglobin
Targeted protein degradation as a promising tool for epigenetic upregulation of fetal hemoglobin

Ush-regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis

Lenz, J.; Liefke, R.; Funk, S. F.; Shoup, S.; Nist, A.; Stiewe, T.; Schulz, R.; Tokusumi, Y.; Albert L.; Raifer, H.; Förstemann,K.; Vázquez, O.; Tokusumi,T; Fossett; N.; Brehm, A.*

PLoS Genet., 2021, 17, e1009318

Ush-regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis

Bioorthogonal turn-on BODIPY-peptide photosensitizers for tailored photodynamic therapy

Linden, G.; Vázquez, O.*

Chemistry, 2020, 26, 10014-10023

Contribution to the Special Young Chemists 2020 Themed Issue in Chemistry-A European Journal

Bioorthogonal turn-on BODIPY-peptide photosensitizers for tailored photodynamic therapy

Spicing up an interdisciplinary chemical biology course with the authentic big picture of epigenetic research

Heinrich, B.; Graulich, N; Vázquez, O.*

J. Chem. Educ.., 2020, 97, 1316-1326

ACS Editor’s Choice

Spicing up an interdisciplinary chemical biology course with the authentic big picture of epigenetic research

4-Methyltrityl-protected pyrrole and imidazole building blocks for solid phase synthesis of DNA-binding polyamides

Heinrich, B.; Vázquez, O.*

Org. Lett., 2020, 22, 533-536

4-Methyltrityl-protected pyrrole and imidazole building blocks for solid phase synthesis of DNA-binding polyamides

In search of visible-light photoresponsive peptide nucleic acids (PNAs) for reversible control of DNA hybridization

Zhang, L.; Linden, G.; Vázquez, O.*

Beilstein J. Org. Chem., 2019, 15, 2500-2508

Contribution to the Special Molecular Switches Themed Issue in Beilstein Journal of Organic Chemistry

In search of visible-light photoresponsive peptide nucleic acids (PNAs) for reversible control of DNA hybridization
1 2 3 Next › Last »