Publications

Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells

Reversible Control of RNA Splicing by Photoswitchable Small Molecules

EFMC: Trends in Medicinal Chemistry and Chemical Biology

Synthesis of the L- and D-SH2 domain of the leukaemia oncogene Bcr-Abl

Increasing the efficiency of hyperthermic intraperitoneal chemotherapy (HIPEC) by a combination with a photosensitive drug in pediatric rhabdomyosarcoma

A chemical biology perspective to therapeutic regulation of RNA splicing in spinal muscular atrophy (SMA)

RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling and nucleosome remodeling

Bistable photoswitch allows in vivo control of hematopoiesis

Efficient antisense inhibition reveals microRNA-155 to restrain a latemyeloid inflammatory programme in primary human phagocytes

Targeted protein degradation as a promising tool for epigenetic upregulation of fetal hemoglobin

Ush-regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis

Bioorthogonal turn-on BODIPY-peptide photosensitizers for tailored photodynamic therapy

Spicing up an interdisciplinary chemical biology course with the authentic big picture of epigenetic research

4-Methyltrityl-protected pyrrole and imidazole building blocks for solid phase synthesis of DNA-binding polyamides

In search of visible-light photoresponsive peptide nucleic acids (PNAs) for reversible control of DNA hybridization

Photoswitchable peptides for spatiotemporal control of biological functions

Conditional singlet oxygen generation via DNA-targeted tetrazine bioorthogonal reaction

Modulating protein-protein interactions with visible-light responsive peptide backbone photoswitches

ortho-Fluoroazobenzene derivatives as DNA intercalators for photocontrol of DNA and nucleosome binding by visible light

A Far-red fluorescent DNA binder for interaction studies of live multidrug-resistant pathogens and host cells

Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia

Potential of proapoptotic peptides to induce formation of giant plasma membrane vesicles with lipide domains

Cytotoxic peptide-PNA conjugates by RNA-programmed peptidyl transfer with turnover

Templated native chemical ligation: peptide chemistry beyond protein synthesis

The ββα fold of zinc finger proteins as a “natural” protecting group. Chemoselective synthesis of a DNA-binding zinc finger derivative

Sequence-selective DNA recognition with peptide-bisbenzamidine conjugates

Straightforward access to bisbenzamidine DNA binders and their use as versatile adaptors for DNA-promoted processes

Light-controlled DNA binding of bisbenzamidines

dsDNA-triggered energy transfer and lanthanide sensitization processes

Bis-4-aminobenzamidines: versatile, fluorogenic A/T selective dsDNA binders

Peptide-based fluorescent biosensors.

Efficient DNA binding and nuclear uptake by distamycin derivates conjugated to octa-arginine sequences

Specific DNA recognition by a synthetic, monomeric Cys2His2 zinc finger peptide conjugated to a minor groove binder

High affinity, sequence specific DNA-binding by synthetic tripyrrole-peptide conjugates