Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells Reported in:
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Reversible Control of RNA Splicing by Photoswitchable Small Molecules |
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EFMC: Trends in Medicinal Chemistry and Chemical Biology |
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Synthesis of the L- and D-SH2 domain of the leukaemia oncogene Bcr-Abl |
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Increasing the efficiency of hyperthermic intraperitoneal chemotherapy (HIPEC) by a combination with a photosensitive drug in pediatric rhabdomyosarcoma Pediatr. Blood Cancer, 2022, 11, e29864 |
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A chemical biology perspective to therapeutic regulation of RNA splicing in spinal muscular atrophy (SMA) |
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RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling and nucleosome remodeling |
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Bistable photoswitch allows in vivo control of hematopoiesis |
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Efficient antisense inhibition reveals microRNA-155 to restrain a latemyeloid inflammatory programme in primary human phagocytes |
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Targeted protein degradation as a promising tool for epigenetic upregulation of fetal hemoglobin Contribution to the Special Chemical Epigenetics Themed Issue in ChemMedChem | ![]() |
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Ush-regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis |
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Bioorthogonal turn-on BODIPY-peptide photosensitizers for tailored photodynamic therapy Contribution to the Special Young Chemists 2020 Themed Issue in Chemistry-A European Journal |
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Spicing up an interdisciplinary chemical biology course with the authentic big picture of epigenetic research ACS Editor’s Choice |
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4-Methyltrityl-protected pyrrole and imidazole building blocks for solid phase synthesis of DNA-binding polyamides |
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In search of visible-light photoresponsive peptide nucleic acids (PNAs) for reversible control of DNA hybridization Contribution to the Special Molecular Switches Themed Issue in Beilstein Journal of Organic Chemistry |
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Photoswitchable peptides for spatiotemporal control of biological functions Contribution to the Special Emerging Investigators Themed Issue in Chemical Communications |
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Conditional singlet oxygen generation via DNA-targeted tetrazine bioorthogonal reaction Highlight as a Hot Paper Reported in local press (Oberhessische Presse, 16.09.2019) Marburg University (09.09.2019) | ![]() |
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Modulating protein-protein interactions with visible-light responsive peptide backbone photoswitches Contribution to the Special ChemBioTalents Themed Issue in ChemBioChem 2019 top downloaded ChemBioChem papers | ![]() |
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ortho-Fluoroazobenzene derivatives as DNA intercalators for photocontrol of DNA and nucleosome binding by visible light Contribution to the Special New Talent Themed Issue in Organic & Biomolecular Chemistry |
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A Far-red fluorescent DNA binder for interaction studies of live multidrug-resistant pathogens and host cells |
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Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia |
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Potential of proapoptotic peptides to induce formation of giant plasma membrane vesicles with lipide domains |
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Cytotoxic peptide-PNA conjugates by RNA-programmed peptidyl transfer with turnover |
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Templated native chemical ligation: peptide chemistry beyond protein synthesis |
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The ββα fold of zinc finger proteins as a “natural” protecting group. Chemoselective synthesis of a DNA-binding zinc finger derivative |
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Sequence-selective DNA recognition with peptide-bisbenzamidine conjugates |
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Straightforward access to bisbenzamidine DNA binders and their use as versatile adaptors for DNA-promoted processes |
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Light-controlled DNA binding of bisbenzamidines |
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dsDNA-triggered energy transfer and lanthanide sensitization processes |
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Bis-4-aminobenzamidines: versatile, fluorogenic A/T selective dsDNA binders |
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Peptide-based fluorescent biosensors. |
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Efficient DNA binding and nuclear uptake by distamycin derivates conjugated to octa-arginine sequences |
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Specific DNA recognition by a synthetic, monomeric Cys2His2 zinc finger peptide conjugated to a minor groove binder |
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High affinity, sequence specific DNA-binding by synthetic tripyrrole-peptide conjugates |
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