Synthesis of the L- and D-SH2 domain of the leukaemia oncogene Bcr-Abl RSC Chem. Biol., 2022, accepted |
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Increasing the efficiency of hyperthermic intraperitoneal chemotherapy (HIPEC) by a combination with a photosensitive drug in pediatric rhabdomyosarcoma |
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A chemical biology perspective to therapeutic regulation of RNA splicing in spinal muscular atrophy (SMA) |
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RNA inhibits dMi-2/CHD4 chromatin binding and nucleosome remodeling and nucleosome remodeling |
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Bistable photoswitch allows in vivo control of hematopoiesis | |
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Efficient antisense inhibition reveals microRNA-155 to restrain a latemyeloid inflammatory programme in primary human phagocytes | |
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Ush-regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis | |
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Targeted protein degradation as a promising tool for epigenetic upregulation of fetal hemoglobin MedChemMed, 2020, 15, 2436-2443 Contribution to the Special Chemical Epigenetics Themed Issue in ChemMedChem |  |
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Bioorthogonal turn-on BODIPY-peptide photosensitizers for tailored photodynamic therapy Chemistry, 2020, 26, 10014-10023 Contribution to the Special Young Chemists 2020 Themed Issue in Chemistry-A European Journal |
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Spicing up an interdisciplinary chemical biology course with the authentic big picture of epigenetic research |
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4-Methyltrityl-protected pyrrole and imidazole building blocks for solid phase synthesis of DNA-binding polyamides |
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In search of visible-light photoresponsive peptide nucleic acids (PNAs) for reversible control of DNA hybridization Beilstein J. Org. Chem., 2019, 15, 2500-2508 |
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Photoswitchable peptides for spatiotemporal control of biological functions Chem. Commun., 2019, 55, 10192-10213 |
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Conditional singlet oxygen generation via DNA-targeted tetrazine bioorthogonal reaction Angew. Chem. Int. Ed. Engl. , 2019, 58,12868-12873 Highlight as a Hot Paper |  |
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Modulating protein-protein interactions with visible-light responsive peptide backbone photoswitches ChemBioChem, 2019, 20, 1417-1429.Contribution to the Special ChemBioTalents Themed Issue in ChemBioChem 2019 top downloaded ChemBioChem papers |  |
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ortho-Fluoroazobenzene derivatives as DNA intercalators for photocontrol of DNA and nucleosome binding by visible light Org. Biomol. Chem., 2019, 17, 1827-1833Contribution to the Special New Talent Themed Issue in Organic & Biomolecular Chemistry |
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A Far-red fluorescent DNA binder for interaction studies of live multidrug-resistant pathogens and host cells Angew. Chem. Int. Ed. Engl., 2018, 57, 11564-11568 |
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Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia Chem. Sci., 2017, 8, 4612-4618 |
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Potential of proapoptotic peptides to induce formation of giant plasma membrane vesicles with lipide domains ChemBioChem., 2015, 16, 1288-1292 |
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Templated native chemical ligation: peptide chemistry beyond protein synthesis J. Pept., 2014, 20, 78-86 |
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The ββα fold of zinc finger proteins as a “natural” protecting group. Chemoselective synthesis of a DNA-binding zinc finger derivative Chem. Commun, 2014, 50, 2258-2260 |
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Straightforward access to bisbenzamidine DNA binders and their use as versatile adaptors for DNA-promoted processes Chem. Sci, 2012, 3, 2383-2387 |
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Bis-4-aminobenzamidines: versatile, fluorogenic A/T selective dsDNA binders Org. Lett. 2010, 12, 216-219 |
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Peptide-based fluorescent biosensors. Chem. Soc. Rev. 2009, 38, 3348-3359 |
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Efficient DNA binding and nuclear uptake by distamycin derivates conjugated to octa-arginine sequences ChemBioChem. 2008, 9, 2822-2829 |
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Specific DNA recognition by a synthetic, monomeric Cys2His2 zinc finger peptide conjugated to a minor groove binder Angew. Chem. Int. Ed. Engl., 2007, 46, 6886–6890 |
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